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1997 2
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FABP2 Ala54Thr genotype is associated with glucoregulatory function and lipid oxidation after a high-fat meal in sedentary nondiabetic men and women.
Weiss EP, Brandauer J, Kulaputana O, Ghiu IA, Wohn CR, Phares DA, Shuldiner AR, Hagberg JM. Weiss EP, et al. Am J Clin Nutr. 2007 Jan;85(1):102-8. doi: 10.1093/ajcn/85.1.102. Am J Clin Nutr. 2007. PMID: 17209184 Free article.
OBJECTIVE: We tested the hypothesis that, in sedentary nondiabetic subjects following a low-fat diet, Thr54 FABP2 carriers have lower glucoregulatory function, greater postprandial lipemia, and greater lipid oxidation rates than do their Ala54 FABP2-homozygous count …
OBJECTIVE: We tested the hypothesis that, in sedentary nondiabetic subjects following a low-fat diet, Thr54 FABP2 carriers have lower …
Quantile-dependent expressivity of postprandial lipemia.
Williams PT. Williams PT. PLoS One. 2020 Feb 26;15(2):e0229495. doi: 10.1371/journal.pone.0229495. eCollection 2020. PLoS One. 2020. PMID: 32101585 Free PMC article.
RESULTS: Consistent with the phenomenon, genetic effect sizes increased (P0.05) with increasing triglyceride concentrations for polymorphisms associated with ABCA1, ANGPTL4, APOA1, APOA2, APOA4, APOA5, APOB, APOC3, APOE, CETP, FABP2, FATP6, GALNT2, GCKR, HL, IL1b, LEPR, LO …
RESULTS: Consistent with the phenomenon, genetic effect sizes increased (P0.05) with increasing triglyceride concentrations for polymorphism …
Regulation of postprandial lipemia: an update on current trends.
Paglialunga S, Cianflone K. Paglialunga S, et al. Appl Physiol Nutr Metab. 2007 Feb;32(1):61-75. doi: 10.1139/h06-100. Appl Physiol Nutr Metab. 2007. PMID: 17332785 Review.
The effects of dietary factors and other meal components on postprandial lipemia leads to the following question: do we need a standardized oral lipid tolerance test (OLTT)? An overview of recent findings on FABP2, MTP, LPL, apoAV, and ASP and the effects of body habitus ( …
The effects of dietary factors and other meal components on postprandial lipemia leads to the following question: do we need a standardized …
Glycosaminoglycan from Ostrea rivularis attenuates hyperlipidemia and regulates gut microbiota in high-cholesterol diet-fed zebrafish.
Kong Y, Li Y, Dai ZR, Qin M, Fan HL, Hao JG, Zhang CX, Zhong QP, Qi C, Wang P. Kong Y, et al. Food Sci Nutr. 2021 Jul 26;9(9):5198-5210. doi: 10.1002/fsn3.2492. eCollection 2021 Sep. Food Sci Nutr. 2021. PMID: 34532028 Free PMC article.
Hyperlipidemia an immense group of acquired or genetic metabolic disorders that is characterized by an excess of lipids in the bloodstream. ...These findings highlight the potential benefit of implementing OGAG as a dietary supplement to prevent and treat hyperlipidemia
Hyperlipidemia an immense group of acquired or genetic metabolic disorders that is characterized by an excess of lipids in the bloods
Improvement in blood lipid levels by dietary sn-1,3-diacylglycerol in young women with variants of lipid transporters 54T-FABP2 and -493g-MTP.
Yanagisawa Y, Kawabata T, Tanaka O, Kawakami M, Hasegawa K, Kagawa Y. Yanagisawa Y, et al. Biochem Biophys Res Commun. 2003 Mar 21;302(4):743-50. doi: 10.1016/s0006-291x(03)00220-1. Biochem Biophys Res Commun. 2003. PMID: 12646232 Clinical Trial.
All subjects, including some with the hyperlipidemia-prone genotypes Ala54Thr of FABP2 and c-493g of MTP, received DAG or TAG (20 g/day) for 8 weeks. ...CONCLUSION: improvement of serum lipid profiles and visceral fat/total fat ratio (CT) was potentiated by DAG inta …
All subjects, including some with the hyperlipidemia-prone genotypes Ala54Thr of FABP2 and c-493g of MTP, received DAG or TAG …
No association found between the Ala54Thr polymorphism of FABP2 gene and obesity and obesity with dyslipidemia in Japanese schoolchildren.
Endo K, Yanagi H, Hirano C, Hayakawa Y, Hamaguchi H, Tomura S. Endo K, et al. J Atheroscler Thromb. 2001;8(3):80-3. doi: 10.5551/jat1994.8.80. J Atheroscler Thromb. 2001. PMID: 11866034
The odds ratio (95% CI) in dyslipidemia of the Thr54 allele was 1.1 (0.8-1.4) in the morbidly obese group. Our data suggested that Ala54Thr polymorphism of the FABP2 gene is not a major contributing factor for obesity and obesity with dyslipidemia in Japanese children....
The odds ratio (95% CI) in dyslipidemia of the Thr54 allele was 1.1 (0.8-1.4) in the morbidly obese group. Our data suggested that Ala54Thr …
Clinical and genetic associations with hypertriglyceridemic waist in a Canadian aboriginal population.
Pollex RL, Hanley AJ, Zinman B, Harris SB, Hegele RA. Pollex RL, et al. Int J Obes (Lond). 2006 Mar;30(3):484-91. doi: 10.1038/sj.ijo.0803152. Int J Obes (Lond). 2006. PMID: 16276364
Subjects were genotyped for HNF1A codon 319, angiotensinogen (AGT) codons 174 and 235, G-protein beta3-subunit (GNB3) nucleotide 825, fatty acid-binding protein (FABP2) codon 54, nucleotides -455 and -482 of the apolipoprotein (apo) C-III (APOC3) promoter, and a 5-bp inser …
Subjects were genotyped for HNF1A codon 319, angiotensinogen (AGT) codons 174 and 235, G-protein beta3-subunit (GNB3) nucleotide 825, fatty …
The association of fatty acid-binding protein 2 A54T polymorphism with postprandial lipemia depends on promoter variability.
Helwig U, Rubin D, Klapper M, Li Y, Nothnagel M, Fölsch UR, Döring F, Schreiber S, Schrezenmeir J. Helwig U, et al. Metabolism. 2007 Jun;56(6):723-31. doi: 10.1016/j.metabol.2006.11.014. Metabolism. 2007. PMID: 17512303
Studies on the association of fatty acid-binding protein 2 (FABP2) A54T and promoter polymorphism, and type 2 diabetes mellitus, insulin, and triglyceride levels are controversial. ...When calculated independently from promoter variability, postprandial triglyceride levels …
Studies on the association of fatty acid-binding protein 2 (FABP2) A54T and promoter polymorphism, and type 2 diabetes mellitus, insu …
Molecular mechanisms of ezetimibe-induced attenuation of postprandial hypertriglyceridemia.
Sandoval JC, Nakagawa-Toyama Y, Masuda D, Tochino Y, Nakaoka H, Kawase R, Yuasa-Kawase M, Nakatani K, Inagaki M, Tsubakio-Yamamoto K, Ohama T, Matsuyama A, Nishida M, Ishigami M, Komuro I, Yamashita S. Sandoval JC, et al. J Atheroscler Thromb. 2010 Sep 30;17(9):914-24. doi: 10.5551/jat.4929. Epub 2010 Jun 11. J Atheroscler Thromb. 2010. PMID: 20543519 Free article.
We have recently reported that ezetimibe inhibits PHTG in patients with type IIb hyperlipidemia. Ezetimibe was also reported to atten-uate PHTG in combination with low-dose statins in patients with obesity or metabolic syndrome. ...The quantitative RT-PCR of intestinal muc …
We have recently reported that ezetimibe inhibits PHTG in patients with type IIb hyperlipidemia. Ezetimibe was also reported to atten …
23 results